尚华,王仁平,黄涛,等.不同剂量有氧运动对成年超重/肥胖患者肝脏脂肪及内脏脂肪含量的影响[J].中华物理医学与康复杂志,2026,48(4):335-341
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| 不同剂量有氧运动对成年超重/肥胖患者肝脏脂肪及内脏脂肪含量的影响 |
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| DOI：10.3760/cma.j.cn421666-20250924-00829 |
| 中文关键词: 有氧运动 运动剂量 超重/肥胖 肝脏脂肪 内脏脂肪 |
| 英文关键词: Aerobic exercise Exercise dosage Overweight Obesity Liver fat Visceral adiposity |
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| 中文摘要: |
| 目的 探讨不同剂量（包括运动强度、运动时间、频次）有氧运动干预对超重/肥胖成年人肝脏脂肪及内脏脂肪含量的影响。 方法 采用随机数字表法将80例无规律运动习惯的成年超重/肥胖患者分为4组，分别是低强度高运动量组［LoHi组，50%最大摄氧量（VO2max），每次运动60 min，每周运动5次］、高强度低运动量组（HiLo组，70%VO2max，每次运动45 min，每周运动3次）、低强度低运动量组（LoLo组，50%VO2max，每次运动45 min，每周运动3次）和对照组（Con组），每组20例，干预时间为8周。于干预前、干预8周后采用氢质子磁共振波谱法（1H-MRS）检测各组患者肝脏脂肪含量，采用计算机断层扫描（CT）测定内脏脂肪含量，采用递增负荷运动试验测定患者VO2max，同时检测患者血清转氨酶含量变化。 结果 与干预前比较，干预后LoHi组、HiLo组、LoLo组肝脏及内脏脂肪含量均明显下降（P<0.05），VO2max则显著升高（P<0.05），体重、体重指数（BMI）及血清转氨酶含量均无明显变化（P>0.05），Con组上述各项指标亦无明显变化（P>0.05）；通过组间比较发现，干预后LoHi组、HiLo组、LoLo组肝脏、内脏脂肪含量及VO2max组间差异仍无统计学意义（P>0.05），且均优于Con组相应水平（P<0.05）。 结论 8周不同剂量有氧运动均可显著降低成年超重/肥胖患者肝脏脂肪及内脏脂肪含量，且该临床获益不依赖于体重减轻，具有较好的可行性及安全性。 |
| 英文摘要: |
| Objective To document the effects of different intensities, durations and frequencies of aerobic exercise on liver fat and visceral fat among overweight or obese adults. Methods Eighty sedentary adults who were overweight or obese were randomly assigned to either a low-intensity high-volume group (LoHi: 50% VO2max, 60 min/session, 5 sessions/week), a high-intensity low-volume group (HiLo: 70% VO2max, 45 min/session, 3 sessions/week), a low-intensity low-volume group (LoLo: 50% VO2max, 45 min/session, 3 sessions/week), or a no-exercise control group (Con). All the groups were administered with respective aerobic exercise protocols accordingly. There were 20 in each group. The intervention lasted for 8 weeks. Before and after the intervention, liver fat was measured using hydrogen proton magnetic resonance spectroscopy, visceral fat content was quantified using computed tomography, VO2max through a graded exercise test, and serum transaminase levels using an automatic biochemical analyzer. Results Compared with baseline, liver and visceral fat decreased significantly and VO2max increased significantly in the LoHi, HiLo, and LoLo groups, though there was no significant change in body weight, body mass index (BMI) or serum transaminase levels, on average. No significant changes were observed in the Con group. Inter-group comparison showed that there was no significant difference in liver or visceral fat, or in VO2max among the LoHi, HiLo, and LoLo groups after the intervention. All of those indicators were, however, superior to those of the Con group (P≤0.05). Conclusions Eight weeks of aerobic exercise can reduce liver and visceral fat for overweight and obese adults, and this effect is independent of weight loss. The treatment has good feasibility and safety. |
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