许航瑞,尹景晖,罗美玲,等.分心干扰对不同偏瘫侧别脑卒中患者执行运动想象任务时大脑功能的影响[J].中华物理医学与康复杂志,2026,48(4):298-304
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| 分心干扰对不同偏瘫侧别脑卒中患者执行运动想象任务时大脑功能的影响 |
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| DOI：10.3760/cma.j.cn421666-20250427-00368 |
| 中文关键词: 脑卒中 运动想象 脑电图 分心 功能连接 |
| 英文关键词: Stroke Motor imagery Electroencephalography Distraction Functional brain connectivity |
| 基金项目:山东省泰山学者特聘专家项目 (tstp2023065)；国家重点研发计划 “主动健康和人口老龄化科技应对” 重点专项 (2023YFC3604502)；国家自然科学基金资助项目 (82172536) |
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| 中文摘要: |
| 目的 探究分心干扰对不同偏瘫侧别脑卒中患者执行运动想象任务时大脑功能的影响。 方法 选取30例脑卒中后偏瘫患者，根据偏瘫侧别分为左侧偏瘫组和右侧偏瘫组，每组15例。另选取15例健康成年人作为对照组。所有受试者在无分心任务干扰及有分心任务干扰（闭眼、听新闻、屏幕闪烁、振动）下执行右手运动想象任务。采用功率谱密度量化前运动皮质（PMC）与初级运动皮质（M1）的激活强度，通过Pearson相关系数分析功能连接（FC）变化，并运用独立样本t检验与方差分析比较组间差异。 结果 在无分心任务干扰下，右侧偏瘫患者患侧PMC与M1的激活程度显著高于对照组（P<0.05）；闭眼、听新闻的分心任务干扰会显著降低偏瘫患者双侧脑区的激活程度及FC（P<0.05），且左侧偏瘫患者的FC对分心干扰更为敏感。对照组脑区活动及FC在分心任务干扰下无显著变化（P>0.05）。 结论 闭眼、听新闻的分心干扰任务会削弱脑卒中偏瘫患者运动想象相关脑区（PMC-M1）的激活程度及FC，且左侧偏瘫患者的FC对分心干扰更为敏感。 |
| 英文摘要: |
| Objective To determine the effect of distractive interference on brain function when stroke survivors perform a motor imagery(MI) task. Methods Thirty hemiplegic stroke survivors were divided into left-and right-sided hemiplegia groups(15 in each), along with 15 healthy adults. All performed right-hand MI tasks without distraction and with the eyes closed, and then distracted by news playback, a flashing screen, or vibration. Power spectral density(PSD) was used to quantify activation intensity in the premotor cortex(PMC) and the primary motor cortex(M1). Changes in functional connectivity(FC) were analyzed. Independent sample t-tests and analysis of variance(ANOVA) were applied to compare intergroup differences. Results With no distraction, activation in the affected PMC and M1 was significantly higher in those with right-side hemiplegia than among the healthy controls. Closed eyes and the news broadcast significantly reduced bilateral brain activation and FC in the hemiplegic subjects, with left-sided hemiplegia correlated with greater FC sensitivity to distractions. A flashing screen or vibration generated no consistent significant changes in brain activity or FC. Conclusions A distractive news broadcast or closing the eyes attenuates activation and functional connectivity in the MI-related brain regions(PMC-M1) of hemiplegic stroke survivors. Left-sided hemiplegia predicts greater sensitivity to distraction. |
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